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Carbazochrome sodium sulfonate is a medicine available in a number of countries worldwide. The effects of carbazochrome sodium sulfonate ac17, a capillary stabilizer, on pulmonary edema and dysfunction induced by ioxaglate, an ionic radiographic contrast medium, were evaluated in rats. In the future this may prevent excessive blood flow during surgical operations and the treatment of hemorrhoids, but research on effectiveness and severity of side effects remains inconclusive. Disclosed is a hemostatic injection of carbazochrome sodium sulfonate and method for preparation, wherein the injection comprises carbazochrome sodium sulfonate 0. Sodium hydroxymethanesulfonate formaldehyde bisulfite. Please use the form above to make an enquiry about cas 51019, carbazochrome sodium sulfonate trihydrate remembering to include the information regarding purity and the quantity you require. Jun 25, 2014 to study the effect of carbazochrome sodium sulfonate, an agent that reduces capillary permeability, on refractory chronic prostatitis. Purchase or get carbazochrome sodium sulfonate price. Sulfonates are the conjugate base of sulfonic acids. Carbazochrome is an antihemorrhagic, or hemostatic, agent that will cease blood flow by causing the aggregation and adhesion of platelets in the blood to form a platelet plug, ceasing blood flow from an open wound. Sodium, calcium and barium sulfonates lockhart chemical company is a global leader in the manufacturing and blending of sodium, calcium and barium sulfonates including their application and uses. Semicarbazide hydrochloride as impurity in drug substances.
Sodium hydroxymethanesulfonate, also known as sodium formaldehyde bisulfite bisulphite, used as a preservative in cosmetic compositions. Carbazochrome sodium sulfonate css reduces bleeding through. It is hoped that this drug can be used in the future for preventing excessive blood flow during surgical operations and the. Patients with prostatitis refractory to at least 8 weeks of routine therapy and with urinalysis positive for. Buy carbazochrome salicylate price, for sale, purchase 51. Sodium styrene sulfonate nass was used as received from air products, inc. Plc ip3dag pathway to increase intracellular free calcium concentration with these subsequent actions. According to the vcrp, there were no reported uses for sodium c1214 olefin sulfonate.
Carbazochrome sodium sulfonate ac17 reverses endothelial. The aim of this randomized prospective study was to clarify risks associated with a drainclamping method using tranexamic acid and carbazochrome sodium sulfonate hydrate after total knee arthroplasty tka. Carbazochrome sodium sulfonate css is a capillary stabilizer that reduces capillary permeability and enhances contraction of broken capillary ends. The sodium preparations most widely used in medicine are sodium sulfate. The determination was optimized and carried out with positive atmospheric pressure chemical ionization by selective reaction monitoring of the ion of mz 148, the protonated thermodegraded fragment of the free acidic form of carbazochrome sodium sulfonate selected as the parent, and the ion of mz 107 as the optimum collision induced. Pharmacokinetics of carbazochrome sodium sulfonate in rabbits given by needle free injection article in journal of chinese pharmaceutical sciences 4720.
Cn102525908a carbazochrome sodium sulfonate pharmaceutical. By merging fresh, new trends with timehonored medicine, natural pharmacy has embraced the changing technology that makes online pharmaceuticals both prescription and overthecounter options popular while finding a way to retain respect for ageold homeopaths that continue to be an essential part of both asian and western medicine. Optimization of solid phase extraction clean up and validation of quantitative determination of carbazochrome sodium sulfonate in human plasma by liquid chromatographyelectrospray ionization tandem mass spectrometry. Sodium dodecyl sulfonate sds, potassium persulfate k2s208, and ndodecylthiol c12sh were used as re ceived. The severity of pain score 010, daytime and nighttime frequency, international prostate symptom score, global selfassessment, urine occult blood positivity, and adverse events were assessed after 4 and 8 weeks of treatment, and compared with baseline findings. Carbazochrome attenuates pulmonary dysfunction induced by. The carbazochrome sodium sulfonate sodium chloride injection is prepared by adopting the formula, and the problems that the carbazochrome sodium sulfonate sodium chloride injection in the prior art cannot tolerate sterilization of which f0 is greater than or equal to 8, and the product is poor in stability in the production and storage processes are solved. Pharmacokinetics of carbazochrome sodium sulfonate in. Tassniyom s, vasanawathana s, dhiensiri t, nisalak a, chirawatkul a j pediatr 1997 oct. Sulfonates are generally stable in water, nonoxidizing, and colorless. Hu x, zheng y, wu g, liu j, zhu m, zhou h, zhai y, wu l, shentu j.
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Carbazochrome sodium sulfonate chemical properties molecular formula of carbazochrome sodium sulfonate cas no. Rust preventive coating sodium sulfonate sonneborn. Hemostatic and antiinflammatory effects of carbazochrome sodium. This injection is formulated by our highly skilled professionals using optimum quality chemical compounds with the aid of advanced methodology. Request pdf on jan 16, 2015, giulio cesare passali and others published an old drug for a new application. Development and validation of a robust lcmsms with atmospheric pressure chemical ionization for quantitation of carbazochrome sodium sulfonate in human plasma. Naxsoft products include alkyl aryl sulfonates and olefin sulfonates. Carbazochrome sodium sulfonate ac17 adrenergic receptor. Sonneborns sodium sulfonates are made from natural petroleum oil feedstocks. Find all the information about carbazochrome sodium sulfonate for cell signaling research. It is used to treat bleeding diseases of the urinary system, upper digestion, respiratory tract, and in obstetrics and gynecology.
Subjects comprised 100 patients scheduled to undergo tka, randomized into 2 groups. Patients with prostatitis refractory to at least 8 weeks of routine therapy and with urinalysis positive for microhematuria were considered for the present study. The pulmonary edema was evaluated by the extravasation of intravenously injected evans blue into lung tissues, while pulmonary dysfunction was. The sodium hydroxymethane sulfonate is used to improve the color stability of rosin resins and it has properties of both formaldehyde and sodium bisulfite. Our offered carbazochrome salicylate injection is a powerful systematic coagulant which is widely used in capillary bleeding during surgery, internal bleeding, bleeding from udder and open wound. Sulfonic acids, c1416alkane hydroxy and c1416alkene, sodium salts. Calsoft aos40 sodium c1416 olefin sulfonate pilot chemical corporation chemical store inc. In addition to their prior therapy, the patients received carbazochrome at a dose of 30 mg three times a day. Nondrainage versus drainage in tourniquetfree knee arthroplasty. Others carbazochrome is an antihemorrhagic agent that will cease blood flow by causing the aggregation and adhesion of platelets in the blood to form a platelet plug, ceasing blood. Carbazochrome adalah obat yang berfungsi untuk menghentikan pendarahan berlebih selama prosedur operasi, pengobatan wasir dan thrombocytopenic purpura, yaitu penyakit dalam darah yang menyebabkan bercak keunguan dan kemerahan pada kulit. Carbazochrome salicylate injection carbazochrome salicylate. Hemostatic injection of carbazochrome sodium sulfonate and.
It is used to treat bleeding diseases of the urinary system, upper digestion, respiratory tract, and in obstetrics and gynecology , 14. Others carbazochrome is an antihemorrhagic agent that will cease blood flow by causing the aggregation and adhesion of platelets in the blood to form a platelet plug, ceasing blood flow from an open wound. Buy carbazochrome sodium sulfonate price, for sale, purchase. Failure of carbazochrome sodium sulfonate ac17 to prevent. Carbazochrome sodium sulfonate c10h11n4nao5s cid 5705561 structure, chemical names, physical and chemical properties, classification, patents. However, it is unclear if it is beneficial and there is concern about possible side effects when it is combined with sorbitol. Effect of carbazochrome sodium sulfonate on refractory chronic. Sonneborns sodium sulfonates possess a structure which is composed of a polyalkylated aromatic ring system, where the alkylates are primarily branched and shortchained.
Aug 20, 2003 the effect of carbazochrome sodium sulfonate ac17, a hemostatic drug with capillary stabilising action, on the endothelial barrier dysfunction induced by a variety of vasoactive substances or agents that increase the vascular permeability was investigated in the monolayers of cultured porcine aortic endothelial cells paecs. The carbazochrome sodium sulfonate oral disintegrating tablets are prepared from the following components in percentage by mass. Resistrationgeneral name therapeutic category cas no. Material safety datasheet sodium c14c16 alpha olefin sulfonate calsoft aos40 product name inci name manufacturer. Buy carbazochrome salicylate price, for sale, purchase. Carbazochrome sodium sulfonate products for sale from biotain pharma co.
The endothelial barrier function was determined by the. The invention relates to a carbazochrome sodium sulfonate pharmaceutical composition, which is prepared from the following components in part by weight. Since a semicarbazone group is present in both the structures of. Failure of carbazochrome sodium sulfonate ac17 to prevent dengue vascular permeability or shock. The invention discloses carbazochrome sodium sulfonate oral disintegrating tablets and a preparation method thereof. Looking for where to buy carbazochrome sodium sulfonate, c10h11n4nao5s, cas no. Buy carbazochrome sodium sulfonate price, for sale. A list of us medications equivalent to carbazochrome sodium sulfonate is available on the website. Carbazochrome is a medicine available in a number of countries worldwide. The broad distribution of molecular weights of the sonneborn petronate sodium sulfonates enhances the ability of the sulfonate to interact with the oil and provides excellent emulsification compared to a synthetic sodium sulfonate of the same molecular weight. Effect of carbazochrome sodium sulfonate on refractory.
It is used as a potassium binder in acute and chronic kidney disease for people with hyperkalemia abnormal high blood serum potassium levels. A list of us medications equivalent to carbazochrome is available on the website. Carbazochrome salicylate definition of carbazochrome. Carbazochrome is an antihemorrhagic, or hemostatic, agent that will cease blood flow by. Sodium dodecylbenzene sulfonate sodium dodecylbenzene sulfonate alphastep pc48 anionics cedepal fa406 ammonium ether sulfate cedephos fa600 alkyl ether phosphate bioterge pas 7s sodium alkane sulfonate bioterge pas8s sodium caprylyl sulfonate ninate 401a calcium alkylbenzene sulfonate, branched ninate 411. It is an oxidation product of adrenaline which enhances the microcirculatory tone.
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